BOTOX® Cosmetic is a simple, nonsurgical, physician-administered treatment that can temporarily smooth moderate to severe frown lines between the brows in people from 18 to 65 years of age. It is the only treatment of its type approved by the Food and Drug Administration (FDA). Although used "off label" botox is also used for transverse forehead lines and crows feet. It is FDA approved to treat excessive sweating or hyperhidrosis.
One 10-minute treatment—a few tiny injections—and within days there's a noticeable improvement in moderate to severe frown lines between the brows, which can last up to 4 months. Results may vary.
BOTOX® Cosmetic is a purified protein produced by the Clostridium botulinum bacterium, which reduces the activity of the muscles that cause those frown lines between the brows to form over time.
In 2005, almost 3.3 million procedures were performed with FDA-approved BOTOX® Cosmetic.
Restylane has been used in more than 3 million treatments in over 70 countries and is now approved in the U.S. for the treatment of facial wrinkles and folds
Restylane is a safe and natural cosmetic dermal filler that restores volume and fullness to the skin to correct facial wrinkles and folds, such as nasolabial folds 
Restylane has a highly favorable safety profile. It is composed of non-animal stabilized hyaluronic acid. Hyaluronic acid is a substance found naturally in the human body. Restylane is fully biocompatible. There is limited risk of animal-based disease transmission or development of allergic reactions to animal proteins. No allergy testing is required before use.*
Restylane maintains its shape using the body's own moisture. The hyaluronic acid in Restylane is hydrophilic or "water loving." As hyaluronic acid gradually degrades, each molecule binds to more water and over time, the same volume can be maintained with less hyaluronic acid. This ability of hyaluronic acid to bind to water is what helps provide long-lasting results.
Unlike rooster-derived hyaluronic acids and bovine collagen products, Restylane is free from animal proteins. This limits any risk of animal-based disease transmissions or development of allergic reactions to animal proteins.
In a simple procedure, Restylane is injected directly into mid-to-deep dermis for long-lasting correction of facial wrinkles and folds. Results from a typical Restylane treatment have been documented to last for about six months. However, individual results may vary.
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